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Index > Protein center > GAPDH(Gene name) > Pig
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  • GAPDH (Gene name),
  • Glyceraldehyde-3-phosphate dehydrogenase (Protein name ),  G3P_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    GAPDH(GAPD);
    Protein name:
    Glyceraldehyde-3-phosphate dehydrogenase(GAPDH);
    Alternative:
    2.6.99.-;Peptidyl-cysteine S-nitrosylase GAPDH);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Homotetramer. Interacts with EIF1AD, USP25, PRKCI and WARS. Interacts with TPPP; the interaction is direct. Interacts (when S-nitrosylated) with SIAH1; leading to nuclear translocation. Interacts with RILPL1/GOSPEL, leading to prevent the interaction between GAPDH and SIAH1 and prevent nuclear translocation.
    Function:
    Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
    Subcellular Location:
    Cytoplasm cytosol Nucleus Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal.
    Protein Attributes:
    Sequence length:
    333
    Sequence:
    50:
    MVKVGVNGFG | RIGRLVTRAA | FNSGKVDIVA | INDPFIDLHY | MVYMFQYDST | 
    100:
    HGKFHGTVKA | ENGKLVINGK | AITIFQERDP | ANIKWGDAGA | TYVVESTGVF | 
    150:
    TTMEKAGAHL | KGGAKRVIIS | APSADAPMFV | MGVNHEKYDN | SLKIVSNASC | 
    200:
    TTNCLAPLAK | VIHDHFGIVE | GLMTTVHAIT | ATQKTVDGPS | GKLWRDGRGA | 
    250:
    AQNIIPASTG | AAKAVGKVIP | ELNGKLTGMA | FRVPTPNVSV | VDLTCRLEKP | 
    300:
    AKYDDIKKVV | KQASEGPLKG | ILGYTEDQVV | SCDFNSDTHS | STFDAGAGIA | 
    333:
    LNDHFVKLIS | WYDNEFGYSN | RVVDLMVHMA | SKE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Pig GAPDH
    Cat.:
    E1932m
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    96T
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    ELISA Kit for Pig GAPDH
    Cat.:
    E1932h
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    96T
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    ELISA Kit for Pig GAPDH
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    E1932d
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    ELISA Kit for Pig GAPDH
    Cat.:
    E1932r
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    ELISA Kit for Pig GAPDH
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    ELISA Kit for Pig GAPDH
    Cat.:
    E1932p
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    ELISA Kit for Pig GAPDH
    Cat.:
    E1932b
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    96T
    ELISA Kit for Pig GAPDH
    Cat.:
    E1932c
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    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932b
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    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GAPDH
    Cat.:
    U1932h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GAPDH
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    Polyclonal Antibody for Pig GAPDH
    Cat.:
    P1932Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GAPDH
    Cat.:
    P1932Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GAPDH
    Polyclonal Antibody for Pig GAPDH
    Polyclonal Antibody for Pig GAPDH
    Polyclonal Antibody for Pig GAPDH
    Polyclonal Antibody for Pig GAPDH
    Polyclonal Antibody for Pig GAPDH
    Cat.:
    P1932Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Monoclonal Antibody for Pig GAPDH
    Protein for Pig GAPDH
    Protein for Pig GAPDH
    Protein for Pig GAPDH
    Protein for Pig GAPDH
    Cat.:
    R1932h
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Pig GAPDH
    Protein for Pig GAPDH
    Protein for Pig GAPDH
    Protein for Pig GAPDH

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    References
    1. 1.
      "Sus scrofa glyceraldehyde-3-phosphate dehydrogenase, genomic and cDNA sequences."
      Behdjani R. , Silversides D.W.
      Submitted (1997-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Evaluation and characterization of a porcine small intestine cDNA library."
      Winteroe A.K. , Fredholm M.
      Submitted (1997-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-126
      tissue: Small intestine.
    3. 3.
      "Glyceraldehyde 3-phosphate dehydrogenase from pig muscle."
      Harris J.I. , Perham R.N.
      Nature219:1025-1028(1968) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-333
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 46
    5. 5.
      "Structural evidence for a liver-specific glyceraldehyde-3-phosphate dehydrogenase."
      Kulbe K.D. , Jackson K.W. , Tang J.
      Biochem. Biophys. Res. Commun.67:35-42(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-23
      tissue: Liver.
    6. 6.
      Foss D.L. , Murtaugh M.P.
      Submitted (1996-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 15-301
    7. 7.
      "Detection of transcripts for retinoic acid receptors, retinol-binding protein, and transforming growth factors during rapid trophoblastic elongation in the porcine conceptus."
      Yelich J.V. , Pomp D. , Geisert R.D.
      Biol. Reprod.57:286-294(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 174-323
    8. 8.
      "Isolation and characterization of cDNA clones coding for porcine muscle proteins."
      Davoli R. , Zambonelli P. , Fontanesi L. , Bigi D. , Costosi E. , Russo V.
      Submitted (1995-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 299-333
      tissue: Skeletal muscle.
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